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The men were randomised to Weight Watchers weight loss programme plus placebo versus the same weight loss programme plus testosteronetreatment, the latter being the control group. Their dietary advice is shown in . The results showed that men in the weight loss group reduced their dieting by an equal amount. Compared with the placebo group, the weight-loss weight-loss programme was twice as effective in reducing weight (1.06 +/- 0.06 kg) in men, but the weight-loss group experienced a greater decline in HDL-cholesterol levels (0.36 +/- 0.06 mg/dL) which is usually an adverse effect of high cholesterol. Moreover, the weight loss group also had a significantly higher body mass index (BMI) of 25.13 +/- 0.19 kg/m(2) at end of six months than the placebo group. The men were more satisfied with their dieting programme (p < 0.05) and reported more energy to exercise ratio (p < 0.05) after the weight loss and exercise programmes. Both groups appeared to have more energy to exert during the weight loss programme (p < 0.05). Lifestyle factors influencing weight loss, in particular lifestyle interventions, are of increasing interest to epidemiologists. The purpose of this meta-analysis was to investigate the effect of an intensive lifestyle change programme with Weight Watchers weight loss on cardiovascular events such as coronary heart disease (CHD), stroke, stroke–vascular death and death due to cardiovascular disease (CVD), and to analyse the association between these events and diet. The authors hypothesized that men with high rates of dieting have a higher risk of developing CHD, CVD and death due to CVD. A recent meta-analysis suggests that an intensive lifestyle intervention with Weight Watchers weight loss programmes significantly reduces CVD (1). This is further supported with the recent publication from the European Cardiovascular Prevention and Prevention Study (ECTAS), in which a weight loss programme with Weight Watchers weight loss programme with a 3-month weight loss resulted in a significantly lower risk of CVD mortality. It is important to examine the extent to which lifestyle changes impact on risk of developing CVD. Our aim was to investigate the effect of Weight Watchers Weight Watchers weight loss programme with Weight Watchers (WTW) diet on lipid profiles, cardiovascular events and mortality in men, by performing separate analyses in men and women from the European Cardiovascular Prevention and Prevention Study (ECTAS) at the time of randomisation and after one to 12 months, and to address inconsistencies by examining potential risk factors at Similar articles: